Dr. Ramya. S. had completed MBBS from SSMC, Tumkur, Karnataka (RGUHS) and MD (Pharmacology) from KIMS, Bangalore, (RGUHS). Her academic career began with Sri Ramachandra Medical College and Research Institute as an Assistant Professor in 2014 followed by Associate Professor since 2023 till date. During this decade long tenure, she has handled academics, research, clinical and medical education related responsibilities. The posts currently held by her are Programme Director – Phase II MBBS SRMC, Member of NMC CC Committee, FDP committee, Dept of Medical Education, SRIHER, Member of Clinical Trial Institutional Ethics Committee of SRMC & RI, Member Secretary of SAE Subcommittee of Clinical Trial Institutional Ethics Committee of SRMC & RI, Member of Grievance Redressal Committee, SRMC & RI, Clinical Pharmacologist Sri Ramachandra Medical Centre, Acquisition Editor Bridges SRIHER, Department Coordinator NSS, SRIHER. She is certified in 3T- Integrated Bioethics Training Course for Health Sciences Faculty, Advance course in Medical Education and in Educational Course on “Principles and Practice of Clinical Research” conducted by NIH, DBT, BIRAC, CDSA. She was the Recipient of GATE-Young Faculty Research Grant of Sri Ramachandra University 2016 and has been involved in two sponsored clinical trials as co-investigator. To her research credits she has 15 original article publications in national and International journals. She has also served as resource person in many educational conferences/CMEs, and won First Prize for research presentations in 2014, 2015, Best Employee Award 2017 in Sri Ramachandra University and “Teacher excellence award for 2021”and Teacher excellence Team award from Sri Ramachandra Medical College and Research Institute, during September 2022 and 2024 respectively. She has guided several students for SRU summer research fellowships, ICMR STS projects and presently guiding two PhD research scholars and three MD pharmacology Postgraduates
Development of resistance to chemotherapeutic drugs by the tumour cells remains a major challenge in successful cancer treatment. Among the numerous mechanisms implicated in mediating resistance, those altering pH in tumour cells have emerged important.
Two important mechanisms involved in proton exchange and alteration of extracellular tumour pH are brought about by carbonic anhydrase IX and vacuolar ATPase. They make the extracellular pH acidic favouring tumour survival.
Thus, inhibitors of carbonic anhydrase IX and vacuolar ATPase are useful targets for overcoming tumour resistance.
This research work was undertaken to evaluate the combined cytotoxic effects of carbonic anhydrase IX (metoprolol) and vacuolar ATPase (lansoprazole) inhibitors using MCF7 breast cancer cell lines.
Liver being one of the most important organs responsible for metabolism, also makes it an attractive organ for toxicity of innumerable drugs and xenobiotics. Among the several mechanisms implicated in the causation of hepatotoxicity, activation of mitogen-activated protein kinase (MAPK) forms a vital one. Hence this represents an important target to develop drugs that can inhibit MAPK.
In light of the above recently valproic acid was found to induce hepatotoxicity by activation of MAPK and metformin was observed to inhibit MAPK in two independent studies.
Therefore, a study was undertaken to evaluate the hepatoprotective effect of metformin [inhibitor of mitogen activated protein kinase (MAPK)] in valproic acid [activator of mitogen-activated protein kinase (MAPK)] induced liver damage in zebrafish.
“Teacher excellence team award” for UG Curriculum Committee from Sri Ramachandra Medical College and Research Institute, Chennai September 2024
Secured qualifying certificate in Educational Course on “Principles and Practice of Clinical Research” conducted by NIH, DBT, BIRAC, CDSA during April 2018.
Best Employee Award 2017 in Sri Ramachandra University
Prize for Best Oral Presentation on “An in-vitro comparative study of antioxidant activity of pregabalin and gabapentin” during ISLETCON 2015 International Conference on Diabetes Mellitus organized by Sree Balaji Medical College and Hospital, Chennai in July 2015.
First Prize for Best Oral Presentation on “Virtual Screening of Phytochemicals to novel target (HAT) Rtt109 in Pneumocystis Jirovecii” during International Conference on Ethics and Responsible Conduct of Research: Basics and Beyond” organized by Sri Ramachandra Medical College & Research Institute, Chennai and CITI University of Miami, in November 2014.
Life time member of Indian Society for Rational Therapeutics since 2021
Life time member of National Pharmacology and Therapeutics since with ID of LM/TN/2023/100502 since 2023 till date
Life time member of Indian Society for Rational Therapeutics since 2023 with membership ID of LR366
Life member since 2014 till date – with membership ID of TN/23223/1/498/191505/2014-15/L. Periodic CMEs conducted by the organization aids in updating knowledge.