Pharmaceutical Product Development and Evaluation
Our research delves into the design, optimization and development of innovative plant-based drug delivery systems for chronic diseases utilizing the principles statistical Quality by Design. Specifically, we develop dosage forms such as niosomes and in-situ gels for the treatment of breast and skin cancers. Additionally, our research focuses on the development of self-micro emulsifying drug delivery systems, solid lipid nanoparticles, emulgels, nano sponges, nanofibers and bilayer tablets. We also conduct comprehensive characterization of the developed dosage forms, including physico-chemical characterizations, drug release studies and in vivo pharmacokinetic studies.
To mitigate adverse effects of orally administered Naproxen (NAP), a novel topical emulgel incorporating Calendula officinalis (CAL) extract is proposed. The emulgel aims to address arthritic symptoms with reduced systemic side effects. Preparation involves formulating an NAP-CAL oil-in-water emulsion and incorporating it into a gel base. Evaluation encompasses viscosity, bio-adhesive strength, spreadability, in vitro anti-inflammatory efficacy, ex-vivo diffusion, and stability studies.
Tamilnadu Pharmacy Council
Indian Pharmaceutical Association
Association of Pharmaceutical Teachers of India