Specific investigations within this domain encompass the kinome landscape in the context of cancer pathogenesis, the examination of novel marine lipidic small molecules for the inhibition of cancer, and the synthesis of innovative heterocyclic compounds exhibiting specific bioactivities, among others. Bioactive compounds are functionally validated through in vitro assays as well as in zebrafish and murine models. Scientists engaged in this focal area hold numerous patents, primarily pertaining to synthesis methodologies and bioactivity assessments. Advanced technologies, including phosphoproteomics utilizing MS/MS and Python-driven artificial intelligence for drug discovery, serve as primary methodologies for in silico target identification.
