Cytogenetics laboratory

Clinical Cytogeneticist with 23 years of experience and has a distinguished career in research and teaching, particularly in the areas of Radiation Biology and have conducted ground-breaking research in chromosomal aberrations and radiation response.  My research journey began with a strong focus on cytogenetics, which has led to contribute significantly towards several high-impact projects, both as a principal investigator and co-investigator. Throughout my career, I have been actively involved in research, publishing articles and contributing to advancements in the field of Genetics.  I have successfully completed several funded projects funded by DRDO, Delhi and currently working on a project funded by DAE-BRNS.

I am Associate Professor at the department of Human Genetics, involved in teaching Undergraduates, Post graduates and internship students.  Part of a genetics diagnostic team with technical expertise on Cytogenetics I have trained academician and students on karyotyping.  Research Domain is on Clinical Cytogenetics, Biodosimetry and Reproductive Genetics

Team: 

Lekha Priya T., (Ph.D., Student): Lekha is working in the field of effect of plant extracts as radioprotectors.

Chandra Lekha A.S. (Ph.D., student): Chandra is working in the field of radiation effects on PBL induced ny radiological procedures. 

Ph.D., and internship opportunities in Chemo/protective efficacy of antioxidant and Reproductive medicine.

Current Projects:

 

Comparison of dose response curve of 60 Co, gamma X-ray induced cytogenetic markers (Manual/Automation)- DAE BRNS funded project Major (On-going)

Publications:

  1. Yugesh, K., Vyas, J.M.V. and Vijayalakshmi, J., 2024. Genotoxicity of Formaldehyde: Effect of Whole-Body Exposure on Polychromatic Erythrocyte/Normochromatic Erythrocyte Ratio in Male and Female Rats. Cureus16(6).
  2. Vijayalakshmi, J., Chaurasia, R.K., Srinivas, K.S., Vijayalakshmi, K., Paul, S.F., Bhat, N.N. and Sapra, B.K., 2023. Establishment of ex vivo calibration curve for X-ray induced “dicentric+ ring” and micronuclei in human peripheral lymphocytes for biodosimetry during radiological emergencies, and validation with dose blinded samples. Heliyon, 9(6).
  3.  Archana, S., Vijayalakshmi, J., Usha Rani, G., Paul, S.F., Reddy, S. and Manjula, G.,2022. The comparison of Y chromosome micro deletion incidence in blood DNA and sperm cell DNA. Molecular Biology Reports, pp.1-6.
  4. Archana.S, G. Siva Krishna, Vijayalakshmi, Devika Gunasheela (2020) (21-4. Acta Scientific pediatrics. Pregnancy outcome in fresh and frozen embryo transfer in women with high estrdiol levels.
  5.  Aswathy S. Lal, S. Kauser Begum, Sraddha S. Bharadwaj, Lalitha V., Vijayalakshmi J., Solomon F.D. Paul, Ravi Maddaly1. Toxicology in Vitro. Volume 54, February 2019, Pages 367-374. Bleomycin-induced genotoxicity in vitro in human peripheral blood lymphocytes evidenced as complex chromosome- and chromatid-type aberrations

For full list of publications:

Google Scholar: https://scholar.google.com/citations?user=6oQEgpcAAAAJ&hl=en 

Admissions